This file has been released into the public domain by the copyright holder, its copyright has expired, or it is ineligible for copyright. This applies worldwide.
Note: This tag is obsolete! Don't use this generic template - please use instead:
{{PD-old}} (for works out of copyright where the author has been dead for over 70 years),
{{PD-Art}} (for photos of old paintings and art out of copyright),
This micrograph of brain tissue reveals the cytoarchitectural histopathologic changes found in bovine spongiform encephalopathy. The presence of vacuoles, i.e. microscopic “holes” in the gray matter, gives the brain of BSE-affected cows a sponge-like appearance when tissue sections are examined in the lab.